Susceptibility of Retinal Vascular Endothelium to Infection withToxoplasma gondiiTachyzoites
Investigative Ophthalmology & Visual Science2004Vol. 45(4), pp. 1157–1157
Citations Over TimeTop 14% of 2004 papers
Justine R. Smith, Daniel Franc, Nicola S. Carter, David O. Zamora, Stephen R. Planck, James T. Rosenbaum
Abstract
Enhanced susceptibility of retinal vascular endothelium to infection by T. gondii tachyzoites may explain, at least in part, preferential localization of T. gondii to the retina. Susceptibility may relate to preferential binding of tachyzoites to the retinal vascular endothelial surface, relative ease of penetration into the cell, rate of replication within the cell and/or cell response to infection.
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