Mitomycin C-Induced Reduction of Keratocytes and Fibroblasts after Photorefractive Keratectomy
Investigative Ophthalmology & Visual Science2004Vol. 45(9), pp. 2978–2978
Citations Over TimeTop 10% of 2004 papers
Abstract
MMC is a potent inhibitor of corneal haze induced by PRK. MMC reduced the number of keratocytes and fibroblasts after PRK and UV-B irradiation. Although MMC would improve the clinical results of PRK, it has significant toxicity on corneal keratocytes, which did not disappear until 3 months after PRK.
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