Neuroprotective Effect of Subretinal Implants in the RCS Rat
Investigative Ophthalmology & Visual Science2005Vol. 46(2), pp. 674–674
Citations Over TimeTop 10% of 2005 papers
Machelle T. Pardue, M. Phillips, Hang Yin, Brian D. Sippy, Sarah Webb-Wood, Alan Y. Chow, Sherry L. Ball
Abstract
These results suggest that subretinal electrical stimulation provides temporary preservation of retinal function in the RCS rat. In addition, implantation of an active or inactive device into the subretinal space causes morphologic preservation of photoreceptors in the RCS rat until 8 weeks after surgery. Further studies are needed to determine whether the correlation of neuropreservation with subretinal implantation is due to electrical stimulation and/or a mechanical presence of the implant in the subretinal space.
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