Gene and Protein Expression Changes in Human Trabecular Meshwork Cells Treated with Transforming Growth Factor-
Investigative Ophthalmology & Visual Science2004Vol. 45(11), pp. 4023–4034
Citations Over TimeTop 10% of 2004 papers
Abstract
Human trabecular meshwork cells can be subjected to increased levels of TGF-beta for several years as a result of glaucoma. The results indicate that changes in extracellular matrix as well as alterations in cytoskeletal proteins occur in these cells as a result of increased TGF-beta. These results are consistent with changes observed in the trabecular meshwork in glaucoma and suggest that at least some of the histologic alterations observed in the meshwork in glaucoma may be the result of increased TGF-betas.
Related Papers
- → Effect of Transforming Growth Factor-beta (TGF-β) on Mammary Development(2003)11 cited
- → Short-or long-term effects of a low-protein diet on fibronectin and transforming growth factor-β synthesis in Adriamycin-induced nephropathy(アドリアマイシン腎症における短期および長期の低蛋白食投与の効果 -フィブロネクチンおよびtransforming growth factor(TGF)-β産生について)(1997)
- The Progress in Researches on TGF-β and its Receptor in Marfan Syndrome(2008)
- Transforming growth factor type beta(TGF—β1 )can increase IL—2R expression and suppress the proliferation of immature(CD~(4-)CD~(8-))thymocytes(1992)