Iris-Derived Cells from Adult Rodents and Primates Adopt Photoreceptor-Specific Phenotypes
Investigative Ophthalmology & Visual Science2005Vol. 46(9), pp. 3411–3411
Citations Over TimeTop 19% of 2005 papers
Tadamichi Akagi, Joe Akita, Masatoshi Haruta, Takuya Suzuki, Yoshihito Honda, Tomoyuki Inoue, Shigeki Yoshiura, Ryoichiro Kageyama, Takaaki Yatsu, Masahiro Yamada, Masayo Takahashi
Abstract
Adult iris-derived cultured cells of both rodents and primates expressed photoreceptor-specific phenotypes by inductions of transcription factors. These iris-derived photoreceptor-like cells have electrophysiological characteristics of rod photoreceptors. Furthermore, they can integrate in the developing retina under coculture conditions.
Related Papers
- → Rhodopsin phosphorylation and its role in photoreceptor function(1998)85 cited
- → Expression of Drosophila rhodopsins during photoreceptor cell differentiation: Insights into R7 and R8 cell subtype commitment(2006)37 cited
- → Calcium‐sensitive control of rhodopsin phosphorylation in the reconstituted system consisting of photoreceptor membranes, rhodopsin kinase and recoverin(1994)54 cited
- → Recoverin inhibits the phosphorylation of dark-adapted rhodopsin more than it does that of bleached rhodopsin: a possible mechanism through which rhodopsin kinase is prevented from participation in a side reaction(1997)26 cited
- → Rhodopsin phosphorylation in bovine rod outer segments is more sensitive to the inhibitory action of recoverin at the low rhodopsin bleaching than it is at the high bleaching(1997)12 cited