Endothelin-1 Enhances Glutamate-Induced Retinal Cell Death, Possibly through ETAReceptors
Investigative Ophthalmology & Visual Science2005Vol. 46(12), pp. 4684–4684
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Takatoshi Kobayashi, Hidehiro Oku, Masayuki Fukuhara, Shota Kojima, Asako Komori, Masaki Ichikawa, Kozo Katsumura, Masato Kobayashi, Tetsuya Sugiyama, Tsunehiko Ikeda
Abstract
These results indicate that ET-1 enhances glutamate-induced retinal cell death, possibly through ET(A) receptors. ET-1 may act synergistically with glutamate to damage retinal neurons under hypoxic conditions.
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