Complement Component 1Q (C1Q) Upregulation in Retina of Murine, Primate, and Human Glaucomatous Eyes
Investigative Ophthalmology & Visual Science2006Vol. 47(3), pp. 1024–1024
Citations Over TimeTop 10% of 2006 papers
Kalliopi Stasi, Dalia Nagel, Xiaoyan Yang, Rongfang Wang, Lizhen Ren, Steven M. Podos, T. Mittag, John Danias
Abstract
Complement expression is upregulated in the retina of two commonly used glaucoma models (in the DBA/2 mouse and the monkey) and in some human glaucomatous eyes. The timing of this upregulation suggests that complement activation plays a significant role in the pathogenesis of glaucoma.
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