RPE65Gene Delivery Restores Isomerohydrolase Activity and Prevents Early Cone Loss inRpe65−/−Mice
Investigative Ophthalmology & Visual Science2006Vol. 47(3), pp. 1177–1177
Citations Over TimeTop 10% of 2006 papers
Abstract
RPE65 gene delivery generates isomerohydrolase activity and restores retinoid profile in Rpe65-/- mice. Regeneration of 11-cis retinal is essential for survival of cone photoreceptors.
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