Complement Factor H Variant Y402H Is a Major Risk Determinant for Geographic Atrophy and Choroidal Neovascularization in Smokers and Nonsmokers
Investigative Ophthalmology & Visual Science2006Vol. 47(2), pp. 536–536
Citations Over TimeTop 1% of 2006 papers
Tiina Sepp, Jane C. Khan, Deborah A. Thurlby, Humma Shahid, David Clayton, Anthony T. Moore, Alan C. Bird, John R.W. Yates
Abstract
The CFH Y402H variant is strongly associated with both GA and CNV in the U.K. population. This association is similar in smokers and nonsmokers. Heavier smokers with the CC genotype may be at particular risk.
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