A Simple, Cross-linked Collagen Tissue Substitute for Corneal Implantation
Investigative Ophthalmology & Visual Science2006Vol. 47(5), pp. 1869–1869
Citations Over TimeTop 10% of 2006 papers
Yuwen Liu, Lisha Gan, David Carlsson, Per Fagerholm, Neil Lagali, Mitchell A. Watsky, Réjean Munger, William Hodge, David H. Priest, May Griffith
Abstract
Collagen can be adequately stabilized, using water soluble carbodiimides as protein cross-linking reagents, in the fabrication of corneal matrix substitutes for implantation. The simple cross-linking methodology would allow for easy fabrication of matrices for transplantation in centers where there is a shortage of corneas, or where there is need for temporary patches to repair perforations in emergency situations.
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