Effects of Topical Administration of Y-39983, a Selective Rho-Associated Protein Kinase Inhibitor, on Ocular Tissues in Rabbits and Monkeys
Investigative Ophthalmology & Visual Science2007Vol. 48(7), pp. 3216–3216
Citations Over TimeTop 10% of 2007 papers
Hideki Tokushige, Masaru Inatani, Shingo Nemoto, Hideyuki Sakaki, Koushirou Katayama, Masayoshi Uehata, Hidenobu Tanihara
Abstract
Y-39983 causes increased outflow facility followed by IOP reduction. Y-39983 ophthalmic solution may be a candidate drug for lowering of IOP, since it increases conventional outflow and produces relatively few side effects.
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