Heritability of Refractive Error and Ocular Biometrics: The Genes in Myopia (GEM) Twin Study
Investigative Ophthalmology & Visual Science2006Vol. 47(11), pp. 4756–4756
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Mohamed Dirani, Matthew Chamberlain, Sri N. Shekar, Amirul Islam, Pam Garoufalis, Christine Y. Chen, Robyn H. Guymer, Paul N. Baird
Abstract
Genetic factors, both additive and dominant, play a significant role in refractive error (myopia and hypermetropia) as well as in ocular biometrics, particularly axial length. The sex limitation ADE model (additive genetic, nonadditive genetic, and environmental components) provided the best-fit genetic model for all parameters.
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