Neuron Stress and Loss Following Rodent Anterior Ischemic Optic Neuropathy in Double-Reporter Transgenic Mice
Investigative Ophthalmology & Visual Science2007Vol. 48(5), pp. 2304–2304
Citations Over TimeTop 10% of 2007 papers
Abstract
Post-ON infarct RGC stress patterns correlate with regional RGC loss. Cellular lacZ levels in most RGCs are low, suggesting rAION-affected RGCs express c-fos only transiently. CFP(+) cell loss correlates closely with quantitative axonal loss, suggesting that the Thy-1 (CFP) transgenic mouse strain is appropriate for RGC stereologic analyses.
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