Stimulation via a Subretinally Placed Prosthetic Elicits Central Activity and Induces a Trophic Effect on Visual Responses
Investigative Ophthalmology & Visual Science2007Vol. 48(2), pp. 916–916
Citations Over TimeTop 11% of 2007 papers
Paul J. DeMarco, Gary L. Yarbrough, Christopher Yee, G. Y. McLean, Botir T. Sagdullaev, Sherry L. Ball, Maureen A. McCall
Abstract
Direct activation of the retina by a subretinal implant induces activity in the SC of RCS rats, suggesting that these implants have some capacity to replace dysfunctional photoreceptors. The data also provide evidence for implant-induced neurotrophic effects as a consequence of both its presence and its activity in the retina.
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