Genetic Polymorphisms in the Promoter of the Interferon Gamma Receptor 1 Gene Are Associated with Atopic Cataracts
Investigative Ophthalmology & Visual Science2007Vol. 48(2), pp. 583–583
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Akira Matsuda, Nobuyuki Ebihara, Naoki Kumagai, Ken Fukuda, Koji Ebe, Koji Hirano, Chie Sotozono, Mamoru Tei, Koichi Hasegawa, Makiko Shimizu, Mayumi Tamari, Kenichi Namba, Shigeaki Ohno, Nobuhisa Mizuki, Zenrō Ikezawa, Taro Shirakawa, Junji Hamuro, Shigeru Kinoshita
Abstract
The -56T allele in the IFNGR1 promoter results in higher IFNGR1 transcriptional activity and represents a genetic risk factor for atopic cataracts.
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