Second-Harmonic Imaging Microscopy of Normal Human and Keratoconus Cornea
Investigative Ophthalmology & Visual Science2007Vol. 48(3), pp. 1087–1087
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Naoyuki Morishige, Andrew Wahlert, M. Cristina Kenney, Donald D. Brown, Koji Kawamoto, Tai-ichiro Chikama, Teruo Nishida, James V. Jester
Abstract
Compared with normal adult corneas, marked abnormalities were detected in the organization of the anterior corneal collagen lamellae of keratoconus corneas by second harmonic imaging. These structural abnormalities are consistent with the known changes in collagen organization and biomechanical strength of keratoconus.
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