Eliminating Complement Factor D Reduces Photoreceptor Susceptibility to Light-Induced Damage
Investigative Ophthalmology & Visual Science2007Vol. 48(11), pp. 5282–5282
Citations Over TimeTop 10% of 2007 papers
Abstract
These results suggest that rod degeneration in the CL-damaged retina involves the activity of the alternative complement pathway and that eliminating the alternative pathway is neuroprotective. Thus, the light damage albino mouse model may be a good model to study complement-mediated photoreceptor degeneration.
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