Retinal Arteriolar Hemodynamic Response to a Combined Isocapnic Hyperoxia and Glucose Provocation in Early Sight-Threatening Diabetic Retinopathy
Investigative Ophthalmology & Visual Science2008Vol. 49(2), pp. 699–699
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Edward D. Gilmore, Chris Hudson, Ravi K. Nrusimhadevara, Rowena Ridout, Patricia T. Harvey, Mark S. Mandelcorn, Wai‐Ching Lam, Robert G. Devenyi
Abstract
The vascular reactivity response to a combined isocapnic hyperoxia and glucose provocation produced a pronounced reduction in blood flow. Unlike the response to hyperoxia alone, the vascular reactivity response was not significantly different across the groups. Hyperglycemia reduced the retinal vascular reactivity response to hyperoxia in age-matched control subjects.
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