Compositional Differences between Infant and Adult Human Corneal Basement Membranes
Investigative Ophthalmology & Visual Science2007Vol. 48(11), pp. 4989–4989
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Andrea Kabosova, Dimitri T. Azar, G. A. Bannikov, Kevin P. Campbell, Madeleine Durbeej, Reza F. Ghohestani, Jonathan Jones, M. Cristina Kenney, Manuel Koch, Yoshifumi Ninomiya, Bruce L. Patton, Mats Paulsson, Yoshikazu Sado, E. Helene Sage, Takako Sasaki, Lydia Sorokin, Marie-France Steiner-Champliaud, Tung‐Tien Sun, Nirmala SundarRaj, Rupert Timpl, Ismo Virtanen, Alexander V. Ljubimov
Abstract
The distribution of laminin gamma3 chain, nidogen-2, netrin-4, matrilin-2, and matrilin-4 is described in the cornea for the first time. The observed differences between adult and infant corneal BMs may relate to changes in their mechanical strength, corneal cell adhesion and differentiation in the process of postnatal corneal maturation.
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