Tauroursodeoxycholic Acid Preservation of Photoreceptor Structure and Function in therd10Mouse through Postnatal Day 30
Investigative Ophthalmology & Visual Science2008Vol. 49(5), pp. 2148–2148
Citations Over TimeTop 14% of 2008 papers
M. Phillips, Tiffany Walker, Hee‐young Choi, Amanda E. Faulkner, Moon Kim, S.S. Sidney, Amber P. Boyd, John M. Nickerson, Jeffrey H. Boatright, Machelle T. Pardue
Abstract
TUDCA is efficacious and safe in preserving vision in the rd10 mouse model of RP when treated between P6 and P30. At P30, a developmental stage at which nearly all rods are absent in the rd10 mouse model of RP, TUDCA treatment preserved rod and cone function and greatly preserved overall photoreceptor numbers.
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