Mutation in a Novel Connexin-like Gene ( Gjf1 ) in the Mouse Affects Early Lens Development and Causes a Variable Small-Eye Phenotype
Investigative Ophthalmology & Visual Science2008Vol. 49(4), pp. 1525–1525
Citations Over TimeTop 16% of 2008 papers
Oliver Puk, Jana Lo ̈ster, Claudia Dalke, Dian Soewarto, Helmut Fuchs, Birgit Budde, Peter Nu ̈rnberg, Eckhard Wolf, Martin Hrabě de Angelis, Jochen Graw
Abstract
The mutated mouse gene belongs to the family of connexin-encoding genes (gene symbols Gja-Gje). Together with its rat and human homologues, it defines a new subgroup, referred to as Gjf1. The mouse mutant described herein offers a new functional candidate gene for microphthalmia-related disorders at the corresponding locus on human chromosome 6, area q24.
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