High-Resolution Spectral Domain-OCT Imaging in Geographic Atrophy Associated with Age-Related Macular Degeneration
Investigative Ophthalmology & Visual Science2008Vol. 49(9), pp. 4137–4137
Citations Over TimeTop 1% of 2008 papers
Monika Fleckenstein, Peter Charbel Issa, Hans‐Martin Helb, Steffen Schmitz-Valckenberg, Robert P. Finger, Hendrik P. N. Scholl, Karin U. Loeffler, Frank G. Holz
Abstract
SD-OCT imaging in eyes with GA revealed a wide spectrum of morphologic alterations, both in the surrounding retinal tissue and in the atrophic area. These alterations may reflect different disease stages or, alternatively, heterogeneity on a cellular and molecular level. Longitudinal studies using in vivo SD-OCT imaging may allow evaluation of the relevance of these phenotypic changes as potential predictive markers for the progression of disease (i.e., enlargement rates of GA over time) and may be used for monitoring of future therapeutic interventions.
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