Targeted Knockout of the Mouse βB2-crystallin Gene (Crybb2) Induces Age-Related Cataract
Investigative Ophthalmology & Visual Science2008Vol. 49(12), pp. 5476–5476
Citations Over TimeTop 24% of 2008 papers
Abstract
BetaB2-crystallin is not essential for the normal development of a transparent lens in the mouse. It plays an increasingly important role in maintaining the transparency of the lens after birth, possibly by interacting with other crystallins to increase their resistance to thermal denaturation and oxidative stress.
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