Effects of Pirfenidone on Proliferation, Migration, and Collagen Contraction of Human Tenon’s Fibroblasts In Vitro
Investigative Ophthalmology & Visual Science2009Vol. 50(8), pp. 3763–3763
Citations Over TimeTop 11% of 2009 papers
Abstract
These findings indicate that pirfenidone inhibits proliferation, migration, and collagen contraction of HTFs at nontoxic concentrations. A decrease in autocrine TGF-beta signaling may have a role in the effects of pirfenidone.
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