Chromosomal Number Aberrations and Transformation in Adult Mouse Retinal Stem Cells In Vitro
Investigative Ophthalmology & Visual Science2009Vol. 50(12), pp. 5975–5975
Citations Over TimeTop 24% of 2009 papers
Meta W. Djojosubroto, F. Bollotte, Pratyaksha Wirapati, Freddy Radtke, Ivan Stamenkovic, Yvan Arsenijévic
Abstract
Adult RSCs rapidly accumulated severe chromosomal aberrations during cultivation, which led to cell transformation in some cell lines. The culture condition plays an important role in supporting the selection and growth of transformed cells.
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