Correction of the Disease Phenotype of Myocilin-Causing Glaucoma by a Natural Osmolyte
Investigative Ophthalmology & Visual Science2009Vol. 50(8), pp. 3743–3743
Citations Over TimeTop 10% of 2009 papers
Abstract
The results indicate that TMAO, with chaperoning activity, facilitated the folding and secretion of mutant MYOC. This therapeutic approach assisted by a chemical chaperone can be developed for treating glaucoma.
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