Spectral Domain Optical Coherence Tomography in Mouse Models of Retinal Degeneration
Investigative Ophthalmology & Visual Science2009Vol. 50(12), pp. 5888–5888
Citations Over TimeTop 10% of 2009 papers
Gesine Huber, Susanne Beck, Christian Grimm, Ayse Sahaboglu, François Paquet‐Durand, Andreas Wenzel, Peter Humphries, T. Michael Redmond, Mathias W. Seeliger, M. Dominik Fischer
Abstract
The authors demonstrated cross-sectional visualization of retinal structures in wild-type mice and mouse models for retinal degeneration in vivo using a commercially available SD-OCT device. This method will help to reduce numbers of animals needed per study by allowing longitudinal study designs and will facilitate characterization of disease dynamics and evaluation of putative therapeutic effects after experimental interventions.
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