Self-complementary AAV Virus (scAAV) Safe and Long-term Gene Transfer in the Trabecular Meshwork of Living Rats and Monkeys
Investigative Ophthalmology & Visual Science2010Vol. 51(1), pp. 236–236
Citations Over TimeTop 10% of 2010 papers
LaKisha K. Buie, Carol A. Rasmussen, Eric C. Porterfield, Vinod S. Ramgolam, Vivian W. Choi, Silva Markovic‐Plese, R. Jude Samulski, Paul L. Kaufman, Teresa Borrás
Abstract
The scAAV viral vector provides prolonged and safe transduction in the trabecular meshwork of rats and monkeys. The stable expression and safe properties of this vector could facilitate the development of trabecular meshwork drugs for gene therapy for glaucoma.
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