Combined Treatment with Bevacizumab and 5-Fluorouracil Attenuates the Postoperative Scarring Response after Experimental Glaucoma Filtration Surgery
Investigative Ophthalmology & Visual Science2010Vol. 51(2), pp. 928–928
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Alicia C. How, Jocelyn Chua, Amanda Charlton, Roseline Su, Marcus Lim, Rajesh S. Kumar, Jonathan G. Crowston, Tina Wong
Abstract
The results provide compelling evidence that combined bevacizumab and 5-FU offers superior antifibrotic effect over monotherapy in a model of glaucoma filtration surgery, while prolonging bleb survival at the same time. A synergistic effect is suggested to be present.
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