Effects of Fasudil, a Rho-Associated Protein Kinase Inhibitor, on Optic Nerve Head Blood Flow in Rabbits
Investigative Ophthalmology & Visual Science2010Vol. 52(1), pp. 64–64
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Tetsuya Sugiyama, Maho Shibata, Sumiko Kajiura, Takashi Okuno, Masahiro Tonari, Hidehiro Oku, Tsunehiko Ikeda
Abstract
These results show that systemic or topical fasudil suppresses impairment of ONH blood flow, function, and morphology induced by L-NAME or ET-1. A ROCK inhibitor can be useful for the treatment of impaired ONH blood flow.
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