Role of CD44+Stem Cells in Mural Cell Formation in the Human Choroid: Evidence of Vascular Instability Due to Limited Pericyte Ensheathment
Investigative Ophthalmology & Visual Science2010Vol. 52(1), pp. 399–399
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Tailoi Chan‐Ling, Mark E. Koina, Janet R. McColm, Jane E. Dahlstrom, Elaine Bean, Sam Adamson, Steven Yun, Louise Baxter
Abstract
CD44+ stem cells are involved in the formation of mural cells in the human choroidal vasculature. A marked reduction in pericyte ensheathment of human choroidal vessels suggests a permanently open "plasticity window" and a predisposition to vascular instability and poor autoregulatory ability.
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