Role of the Adrenergic System in a Mouse Model of Oxygen-Induced Retinopathy: Antiangiogenic Effects of β-Adrenoreceptor Blockade
Investigative Ophthalmology & Visual Science2010Vol. 52(1), pp. 155–155
Citations Over TimeTop 10% of 2010 papers
Chiara Ristori, Luca Filippi, Massimo Dal Monte, Davide Martini, Maurizio Cammalleri, Pina Fortunato, Giancarlo la Marca, Patrizio Fiorini, Paola Bagnoli
Abstract
This is the first demonstration that β-AR blockade is protective against retinal angiogenesis and ameliorates BRB dysfunction in OIR. Although the relevance of these results to infant ROP is uncertain, the findings may help to establish potential pharmacologic targets based on β3-AR pharmacology.
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