Effective and Sustained Delivery of Hydrophobic Retinoids to Photoreceptors
Investigative Ophthalmology & Visual Science2010Vol. 51(11), pp. 5958–5958
Citations Over TimeTop 21% of 2010 papers
Abstract
As a method for sustained drug delivery, subcutaneous administration using Matrigel proved more efficacious than intraperitoneal injection for in vivo delivery of retinoids to cone photoreceptors. These experiments are the first to show a sustained delivery of retinoids in mice and suggest a strategy for potential clinical therapeutic development.
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