Evaluation of Serum Lipid Concentrations and Genetic Variants at High-Density Lipoprotein Metabolism Loci andTIMP3in Age-Related Macular Degeneration
Investigative Ophthalmology & Visual Science2011Vol. 52(8), pp. 5525–5525
Citations Over TimeTop 10% of 2011 papers
Sascha Fauser, Dženita Smailhodzic, Albert Caramoy, Johannes P. H. van de Ven, Bernd Kirchhof, Carel B. Hoyng, B. Jeroen Klevering, Sandra Liakopoulos, Anneke I. den Hollander
Abstract
These results confirm associations of AMD with variants near the TIMP3 gene and at loci involved in HDL metabolism. They further highlight a role of the extracellular matrix and the HDL metabolism in the pathogenesis of AMD. This study identified increased ApoB levels as a possible new serum biomarker for AMD.
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