Studies of Scleral Biomechanical Behavior Related to Susceptibility for Retinal Ganglion Cell Loss in Experimental Mouse Glaucoma
Investigative Ophthalmology & Visual Science2013Vol. 54(3), pp. 1767–1767
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Cathy Nguyen, Frances E. Cone, Thao D. Nguyen, Baptiste Coudrillier, Mary Ellen Pease, Matthew R. Steinhart, Ericka Oglesby, Joan L. Jefferys, Harry A. Quigley
Abstract
Longer eyes, greater scleral strain in some directions at baseline, and generalized scleral thinning after glaucoma were characteristic of CD1 mice that have greater tendency to retinal ganglion cell damage than B6 mice. Increased scleral stiffness after glaucoma exposure in mice mimics findings in monkey and human glaucoma eyes.
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