In Vivo Morphology of the Limbal Palisades of Vogt Correlates With Progressive Stem Cell Deficiency in Aniridia-Related Keratopathy
Investigative Ophthalmology & Visual Science2013Vol. 54(8), pp. 5333–5333
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Neil Lagali, Uri T. Eden, Tor Paaske Utheim, Xiangjun Chen, Ruth Riise, Anette Dellby, Per Fagerholm
Abstract
Progression of limbal stem cell deficiency in aniridia correlates with degradation of palisade structures, gradual transformation of epithelial phenotype, onset of inflammation, and a corneal nerve deficit. IVCM can be useful in monitoring early- to late-stage degenerative changes in stem cell-deficient patients.
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