Noninvasive Imaging of Retinal Morphology and Microvasculature in Obese Mice Using Optical Coherence Tomography and Optical Microangiography
Investigative Ophthalmology & Visual Science2014Vol. 55(2), pp. 1024–1024
Citations Over TimeTop 10% of 2014 papers
Zhongwei Zhi, Jennifer R. Chao, Tomasz Wietecha, Kelly L. Hudkins, Charles E. Alpers, Ruikang K. Wang
Abstract
We conclude that OB BTBR mice have significantly reduced NFL-IPL thicknesses and total RBF rates compared with those of WT mice, as imaged by OCT/OMAG. OMAG provides an unprecedented capability for high-resolution depth-resolved imaging of mouse retinal vessels and blood flow that may play a pivotal role in providing a noninvasive method for detecting early microvascular changes in patients with diabetic retinopathy.
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