Different Hereditary Contribution of theCFHGene Between Polypoidal Choroidal Vasculopathy and Age-Related Macular Degeneration in Chinese Han People
Investigative Ophthalmology & Visual Science2014Vol. 55(4), pp. 2534–2534
Citations Over TimeTop 10% of 2014 papers
Lvzhen Huang, Yingjie Li, Shicheng Guo, Yaoyao Sun, Chunfang Zhang, Yujing Bai, Shanshan Li, Fei Yang, Min Zhao, Min Zhao, Bin Wang, Wenzhen Yu, Mingwei Zhao, Mingwei Zhao, Chiea Chuen Khor, Xiaoxin Li
Abstract
Our data suggest that the genetic architecture at the CFH locus is complex with some markers showing significant skewing of the genotypes toward nAMD or PCV in Asians. This further supports the clinical observation that nAMD and PCV could have distinct pathogenesis mechanisms, which will require larger studies to accurately dissect.
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