Fullerenol Protects Retinal Pigment Epithelial Cells From Oxidative Stress–Induced Premature Senescence via Activating SIRT1
Investigative Ophthalmology & Visual Science2014Vol. 55(7), pp. 4628–4628
Citations Over TimeTop 10% of 2014 papers
Chun-Chun Zhuge, Jingying Xu, Jingfa Zhang, Weiye Li, Peng Li, Zongyi Li, Ling Chen, Xiaoqing Liu, Peng Shang, Hua Xu, Yanjun Lu, Fang Wang, Lixia Lü, Guo‐Tong Xu
Abstract
Fullerenol could rescue RPE cells from oxidative stress-induced senescence through its antioxidation activity and the activation of SIRT1. The protective effect of Fol is useful for the development of new strategies to treat oxidative stress-related retinal diseases like AMD.
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