Nerve Fiber Layer Thinning Lags Retinal Ganglion Cell Density Following Crush Axonopathy
Investigative Ophthalmology & Visual Science2014Vol. 55(10), pp. 6505–6505
Citations Over TimeTop 11% of 2014 papers
Gustavo C. Munguba, Sanja Galeb, Yuan Liu, David C. Landy, Daisy Lam, Andrew Camp, Sinthia Samad, Mary L. Tapia, Richard K. Lee
Abstract
Our data suggest that in vivo CSLO imaging of EYFP-RGC expression and SD-OCT measured NFL thickness are fast and reliable methods that longitudinally track neurodegenerative progression following ONC injury. Neurodegenerative changes in NFL thickness measured by SD-OCT imaging have the same overall trajectory as those observed by CSLO for RCD; however, changes in NFL thickness initially lag behind in vivo RGC soma counts with a slower decline in overall measurable change.
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