Knockout of A-Crystallin Inhibits Ocular Neovascularization
Investigative Ophthalmology & Visual Science2015Vol. 56(2), pp. 816–826
Citations Over TimeTop 14% of 2015 papers
Abstract
Knockout of αA-crystallin inhibited pathologic neovascularization through the VEGF and VEGFR2 signaling pathways both in vitro and in vivo. These results suggest that αA-crystallin could be a novel pharmaceutical target for the prevention of ocular neovascularization.
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