Acetylation Preserves Retinal Ganglion Cell Structure and Function in a Chronic Model of Ocular Hypertension
Investigative Ophthalmology & Visual Science2014Vol. 55(11), pp. 7486–7486
Citations Over TimeTop 22% of 2014 papers
Abstract
Increase in HDAC activity is a relatively early retinal event induced by elevated IOP, and suppressing HDAC activity can protect RGCs from ocular-hypertensive stress. Together these data provide a basis for developing HDAC inhibitors for the treatment of optic neuropathies.
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