M2 Macrophages Enhance Pathological Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy
Investigative Ophthalmology & Visual Science2015Vol. 56(8), pp. 4767–4767
Citations Over TimeTop 13% of 2015 papers
Yedi Zhou, Shigeo Yoshida, Shintaro Nakao, Takeru Yoshimura, Yoshiyuki Kobayashi, Takahito Nakama, Yuki Kubo, Kohta Miyawaki, Muneo Yamaguchi, Keijiro Ishikawa, Yuji Oshima, Koichi Akashi, Tatsuro Ishibashi
Abstract
These results indicated that M2 macrophages, rather than M1, play an important role in promoting retinal pathological neovascularization probably by producing secreted factors. Thus, targeting M2 macrophages could be a potential therapeutic option for inhibiting retinal pathological neovascularization.
Related Papers
- Oxygen-induced retinopathy in the rat: relationship of retinal nonperfusion to subsequent neovascularization.(1994)
- → Antiangiogenic Activity of Aganirsen in Nonhuman Primate and Rodent Models of Retinal Neovascular Disease after Topical Administration(2012)51 cited
- → Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization(2017)16 cited
- → Choroidal Neovascularization Is Provided by Bone Marrow Cells(2004)54 cited
- → Enhancing the research on the mechanism of the occurrence and development of retinal neovascularization to prevent and treat retinal neovascularization diseases(2010)