Axonal Transport in the Rat Optic Nerve Following Short-Term Reduction in Cerebrospinal Fluid Pressure or Elevation in Intraocular Pressure
Investigative Ophthalmology & Visual Science2015Vol. 56(8), pp. 4257–4257
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Zheng Zhang, Danli Liu, Jost B. Jonas, Shen Wu, Jacky M. K. Kwong, Jingxue Zhang, Qian Liu, Lei Li, Qingjun Lu, Diya Yang, Jinda Wang, Ningli Wang
Abstract
Both short-term lowering of CSFP and short-term rise in IOP were associated with a disturbance of both the orthograde and retrograde axonal transport. The findings support the notion of an association between abnormally low CSFP and optic nerve damage.
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