Lipofuscin Redistribution and Loss Accompanied by Cytoskeletal Stress in Retinal Pigment Epithelium of Eyes With Age-Related Macular Degeneration
Investigative Ophthalmology & Visual Science2015Vol. 56(5), pp. 3242–3242
Citations Over TimeTop 1% of 2015 papers
Thomas Ach, Elen Tolstik, Jeffrey D. Messinger, Anna V. Zarubina, Rainer Heintzmann, Christine A. Curcio
Abstract
We report an extensive and systematic en face analysis of LF/MLF-AF in AMD eyes. Redistribution and loss of AF granules are among the earliest AMD changes and could reduce fundus AF signal attributable to RPE at these locations. Data can enhance the interpretation of clinical fundus-AF and provide a basis for future quantitative studies.
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