Subducted and Melanotic Cells in Advanced Age-Related Macular Degeneration Are Derived From Retinal Pigment Epithelium
Investigative Ophthalmology & Visual Science2015Vol. 56(5), pp. 3269–3269
Citations Over TimeTop 10% of 2015 papers
Abstract
'Dissociated' RPE within atrophic areas may be the source of 'Subducted' cells. 'Entombed' RPE within fibrovascular and fibrocellular scars may be the source of 'Melanotic' cells. An imaging correlate for 'Subducted' cells awaits discovery; 'Melanotic' cells appear gray-black in the CNV fundus. Results provide a basis for future molecular phenotyping studies.
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