Metabolome-Wide Association Study of Primary Open Angle Glaucoma
Investigative Ophthalmology & Visual Science2015Vol. 56(8), pp. 5020–5020
Citations Over TimeTop 10% of 2015 papers
L. Goodwin Burgess, Karan Uppal, Douglas I. Walker, Rachel M. Roberson, ViLinh Tran, Megan B. Parks, Emily A. Wade, Alexandra T. May, Allison C. Umfress, Kelli L. Jarrell, Brooklyn Stanley, John Kuchtey, Rachel W. Kuchtey, Dean P. Jones, Milam A. Brantley
Abstract
Global ultrahigh resolution metabolomics emphasized the importance of altered lipid metabolism in POAG. The results suggest specific metabolic processes, such as those involving palmitoylcarnitine, sphingolipids, vitamin D-related compounds, and steroid precursors, may contribute to POAG status and merit more detailed study with targeted methods.
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