Cone Photoreceptor Structure in Patients With X-Linked Cone Dysfunction and Red-Green Color Vision Deficiency
Investigative Ophthalmology & Visual Science2016Vol. 57(8), pp. 3853–3853
Citations Over TimeTop 12% of 2016 papers
Emily J Patterson, Melissa A. Wilk, Christopher S. Langlo, Melissa Kasilian, Michael Gerard Ring, Robert B. Hufnagel, Adam M. Dubis, James Tee, Angelos Kalitzeos, Jessica C. Gardner, Zubair M. Ahmed, Robert A. Sisk, Michael Larsen, Stacy A. Sjoberg, Thomas B. Connor, Alfredo Dubra, Jay Neitz, Alison J. Hardcastle, Maureen Neitz, Michel Michaelides, Joseph Carroll
Abstract
Our findings provide a direct link between disruption of the cone mosaic and L/M opsin variants. We hypothesize that, in addition to large phenotypic differences between different L/M opsin variants, the ratio of expression of first versus downstream genes in the L/M array contributes to phenotypic diversity. While the L/M opsin mutations underlie the cone dysfunction in all of the subjects tested, the color vision defect can be caused either by the same mutation or a gene rearrangement at the same locus.
Related Papers
- Susquehanna Chorale Spring Concert "Roots and Wings"(2017)
- → DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION(2018)
- → Genentech taps Affimed’s antibodies(2018)
- Enxerto livre de arteria epigastrica inferior: avaliacao hemodinamica e angiografica pre e pos-operatoria(1988)
- → KOMPLIKASI REGIONAL ANESTESI PADA PEDIATRIK(2023)