HTRA1 and TGF-β1 Concentrations in the Aqueous Humor of Patients With Neovascular Age-Related Macular Degeneration
Investigative Ophthalmology & Visual Science2017Vol. 58(1), pp. 162–162
Citations Over TimeTop 10% of 2017 papers
Gian Marco Tosi, Elena Caldi, Giovanni Neri, Elisabetta Nuti, Davide Marigliani, Stefano Baiocchi, Claudio Traversi, Gabriele Cevenini, Antonio Tarantello, Fiorella Fusco, Federica Nardi, Maurizio Orlandini, Federico Galvagni
Abstract
In nCNV patients, HTRA1 and TGF-β1 were significantly higher compared to controls. After treatment, TGF-β1 was persistently elevated, while HTRA1 returned to control levels, suggesting the involvement of TGF-β1 and HTRA1 in neovascular AMD and a VEGFA-independent role for TGF-β1.
Related Papers
- → Analysis of ocular fluid in patients with ranibizumab-recalcitrant neovascular age-related macular degeneration who have serum anti-ranibizumab antibodies(2023)4 cited
- → Ranibizumab in Diabetic Macular Edema; Level 1 and Level 2 Studies Findings(2018)1 cited
- Recent advances in intravitreal injection of ranibizumab for myopic choroidal neovascularization(2014)
- → A systematic review of clinical application of ranibizumab in wet age-related macular degeneration(2011)
- → A safety evaluation of ranibizumab in patients with wet age-related macular degeneration(2011)