An Acute Injury Model for the Phenotypic Characteristics of Geographic Atrophy
Investigative Ophthalmology & Visual Science2018Vol. 59(4), pp. AMD143–AMD143
Citations Over TimeTop 10% of 2018 papers
Imran Ahmed Bhutto, Shuntaro Ogura, Rajkumar Baldeosingh, D. Scott McLeod, Gerard A. Lutty, Malia M. Edwards
Abstract
The rat model reported herein mimics the photoreceptor cell loss, RPE atrophy, glial membrane formation, and choriocapillaris degeneration seen in GA. This model will be valuable for developing and testing drugs and progenitor cell regenerative therapies for GA.
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